Thursday, 9 November 2017

Medical Journal- October issue 2017

Medical Journal: Published volume-3, Issue-10, October 2017 with ad publications

Indoor environment: Is it possible to use outdoor air in densely populated areas as an indicator of indoor air quality in Swedish buildings

Abstract— In the last few decades, indoor air problems have increased in Swedish housing, office and school buildings. The problems that are mentioned are mucosal and respiratory symptoms, asthma, skin symptoms, fatigue and headache. In the environmental health report compiled by the responsible authorities, it is shown that the scope of the problem has been constant since the early 1990s. This is done despite the fact that extensive efforts have been made and extensive resources have been used in research, government investigations with new industry directives and through measures taken in buildings. There is a great need for validated analysis and measurement methods, as well as finding level values for the air environment in Swedish housing, office and school buildings. The purpose of this project is to evaluate whether outdoor air can be used as an indicator and level sensor for the quality of the indoor air environment. Outdoor air is an indicator where the number of particles, preferably those larger than 5.0 μm, is a valuable parameter. The long-term goal should be to build a bank with values from the outdoor air. This bank should include values with an even distribution that include temporal variations, the Swedish seasonal variations and the longer-term variations that occur annually. In addition, it should cover a uniform distribution across the whole of Sweden. This bank should be a better basis for assessing the environment in each object, instead of using the value of the level outside the building at the current time of measurement. An important issue is the calibration of measuring instruments to make the results comparable. In this project, this is not a problem since only one and the same instrument is used, but when using several instruments, the relationships actualized.

Keywords: Air quality, Hygiene and Health, Indoor Environment, Particle Amount, Particle Measurements, Particle Size.

Click here to Download Full Paper

___________________________

Effect of Root Heal Therapy (RHT) on Melasma: A Quincy Experiment

Abstract—Melasma is a very common skin disorders which has no fix treatment schedule and is very difficult to treat. This present study was planned to compare the effect of traditional treatment alone and in combination with Root Heal Therapy on Melasma cases. A Quincy experiment was conducted on 60 patients of Melasma, who were taking treatment from a same physician working in Charak Bhawan, a hospital attached to SMS Medical College, Jaipur (Rajasthan). Out of these 67 melasma cases were completed the protocall, out of that 35 were in group who has received traditional treatment, 32 were in group who has received RHT along with traditional treatment. Baseline status of Melasma with its Severity its impact on quality of life was assessed. Severity of Melasma was assessed through MASI scores and quality of life was assessed by Dermatology Life Quality Index (DLQI) scores. These cases were followed for 6 months; again they were assessed as per MASI. Changes in over this period Melasma severity in both the groups were compared with Chi-square test and Unpaired’t’ test. It was found that significantly more cases were benefited with this RHT in the form of number of severity of Melasma and quality of life was also significantly improved with RHT. Further researches are required for further details.

Key Words: Melasma, MASI scores, Dermatology Life Quality Index (DLQI), Root Heal Therapy (RHT).

Click here to Download Full Paper

Saturday, 14 October 2017

Medical Journal- September issue 2017

Medical Journal: Published volume-3, Issue-9, September 2017 with ad publications

Isolated Medial Rectus Cysticercosis mimicking pre-septal cellulitis: A Case Report

Abstract— Man is the intermediate host in the life cycle of the pork tapeworm Taenia solium. Its larval form Cysticercus cellulosae is the causative agent of cysticercosis. Both intraocular and extra ocular cysticercosis is observed in tropical countries like India. A case of extra ocular cysticercosis is reported here. An eight year old female patient who was brought to emergency department with pain and swelling around peri-orbital region, diminution of vision along with ptosis in left eye. CT scan showed scolex of Taenia solium in left medial rectus muscle. The patient recovered completely with oral albendazole steroids for four weeks. So a case with pain and swelling around peri-orbital region, diminution of vision along with ptosis in left eye should be investigated for cysticercosis.

Keywords: Taeniasis, Extra ocular Cysticercosis, Medial Rectus, Peri-Orbital Region.

Click here to Download Full Paper

___________________________

Superior orbital fissure syndrome due to Metastatic prostatic malignancy: A Case Report

Abstract— Superior orbital fissure syndrome (SOFS) is a rare disease. So when a case of this came at Aravind Eye Institute, a detailed case report was prepared to publish. A 56 years old male patient, a known case of prostatic malignancy with skeletal metastasis presented with ptosis, exotropia, diminished pupillary reflex and limitations in extraocular movements of left eye. MRI brain revealed diffuse skull base and leptomeningeal metastasis. Whole body CT scan showed metastasis in ribs, scapula and in pelvic bones. He was diagnosed to have superior orbital fissure syndrome due to metastatic prostatic malignancy and was offered steroids and radiotherapy.

Keywords: Ptosis, Prostate, Metastasis.

Click here to Download Full Paper

___________________________

Clinico-epidemiology and outcome of ectopic pregnancy: An experience of 7 years in St. Stephen’s hospital, Delhi

Abstract— Ectopic pregnancy is an important cause of maternal morbidity & mortality in the first trimester. Treatment of ectopic pregnancy was limited to surgery. In spite of advancement of diagnosis & management it is still a very serious threat to maternal safety, so this case-series type of study was conducted on 58 ectopic pregnancies to study the clinico-epidemiology and outcome of medically managed ectopic pregnancy at a tertiary level hospital. Out of total 20,354 pregnancies, 443 (2.1%) were ectopic pregnancies. Most common site of ectopic pregnancy was Fallopian tubes in 94.8% cases followed by ovary in 3.4% cases and heterotopic in 1.7%. Age range was 17 years to 36 years with mean age 28.12 ± 4.10 years. Parity wise maximam were nulliparous (53.4%) followed by para one (25.9 %), para two (19%) and para three (17.2 %). Ectopic pregnancies on right side were found in 55.2% while in left side in 44.8% 75.8% had bleeding per vaginum and 74.1 % had pain abdomen as their chief complaints. History of abortion was found in 44% cases and past history of ectopic pregnancy was found in 8.6% cases whereas past history of pelvic inflammatory disease in 22.4% cases and infertility in 13.8% cases. 1.7% cases had IUCD in situ while 5.2% cases had history of past IUCD insertion. History of ovulation induction was present in 8.6% cases, 3.4% cases were IVF conceived and 1.7% underwent laparohysteroscopy for infertility treatment. In this study success rate of methotrexate therapy was found 93.1%. Emergency surgery was needed only in 6.9% of cases. So it can be concluded that bleeding per vegina and pain abdomen may be investigated for ectopic pregnancy and ectopic pregnancies should be treated first line with methotrexate before surgery.

Keywords: Ectopic Pregnancy, Methotrexate, Clinico-epidemiology.

Click here to Download Full Paper

____________________________

Clinico-epidemiological study of cutaneous tuberculosis in a tertiary care hospital of Rajasthan

Abstract—India constitutes about one fourth of the Global TB burden. Cutaneous TB is less common clinical form of tuberculosis accounting for 1-2 % of the total extra-pulmonary cases. Objective of this study was to describe the clinical and epidemiological pattern of Cutaneous TB presenting in the Skin Outpatient Department (OPD). Patients presenting with clinically suspected skin lesions of Cutaneous TB from January 2015 to August 2016 were included in the study. Dermatological and systemic examination was carried out and histopathogical examination of skin punch biopsy was done. It was observed that out of a total of sixty patients, 45 (75%) patients were found to have features of Cutaneous TB on histopathology. Lupus vulgaris (42.2%) was the most common form of Cutaneous TB. Most patients were in age group of 11-30 years. Male to female ratio was 1.6:1. Most common sites of involvement were lower limbs and neck. Mantoux test was positive(≥15 mm induration) in 66.7% cases. Typical tuberculoid histology was found in 91.1% cases. No cases of tuberculids were seen and non-specific chronic inflammation was seen in six cases. It was concluded that Cutaneous TB may present with different morphological patterns resembling other inflammatory, infective and neoplastic conditions. Proper and thorough investigations are necessary for detection of Cutaneous TB as the annual incidence of total TB cases in India is high.

Keywords: Cutaneous TB, Lupus vulgaris, Mantoux test, Clinico-epidemiology.

Click here to Download Full Paper

____________________________

Menstrual pattern among school girls with special reference to determinants of amount of menstrual blood loss: A cross-sectional study in Jaipur city

Abstract— Menstruation had many tremendous psychological response in adolescent. And there are many myths prevalent regarding menstruation. So this study was conducted with the aim to study menstrual pattern in adolescent school going girls and association of menstrual blood flow with their BMI, diet, sports activities and gadgets. This study is a descriptive type of cross-sectional study in which adolescent girls who attained menarche were included. Present study was carried out on in government schools Jaipur City (Rajasthan) on 1233 girls aged between 13 to 19 years. BMI was significantly associated with amount of blood loss. Girls whose BMI was <18.5 kg/m2 or underweight had moderate to severe degree of dysmenorrhoea compare to those BMI 18.5-24.9 kg/m2. Proportion of girls involved in sports activities were having less amount of blood loss compared to those who were leading sedentary life. B So it can be concluded that BMI has direct co-relation with menstrual blood loss; the girls involved in sports had less amount of menstrual blood loss.

Keywords: Menstrual Pattern, Menstrual Blood Loss, Adolescence, BMI, Sports Activities.

Click here to Download Full Paper

___________________________

Dosimetric evaluation of carcinoma nasopharynx using Volumetric Modulated Arc Therapy (VMAT): An institutional experience from Western India

Abstract— Treatment of nasopharyngeal carcinoma is done by advanced radiotherapy techniques like VMAT (Volumetric Modulated Arc Therapy) where dose to critical organs around tumour is of concern. Present study aimed to describe radiation dose to critical organs in nasopharyngeal cancer patients using VMAT technique. Study was conducted on 10 carcinoma nasopharynx patients treated by VMAT technique at a super-specialty cancer institute in Rajasthan. The structures were contoured using RTOG (Radiation Therapy Oncology Group) guidelines and dose prescription to PTV (Planning Target Volume) was such that 95% iso-dose covered 100% of PTV. Constraints to the OARs (Organs at risk) were as per QUANTEC (Quantitative Analysis of Normal Tissue Effects in the Clinic). VMAT planning was done by double arc using Eclipse (v 10.0.42) treatment planning system. Mean dose to brain stem, spinal cord and optic chiasma were 51.79 Gy, 45.92 Gy and 18.8 Gy respectively. Mean dose to left and right temporal lobes was 22.7Gy and 24.3Gy. Dose to right and left eye were 20.6 Gy and 19.2 Gy while dose to right and left lenses were 5.9Gy and 5.8 Gy respectively. Dose to brain stem, spinal cord, optic chiasma, eyes, lens and temporal lobes were below the dose constraints. VMAT is an effective way to deliver maximum radiation to tumour tissue while providing better sparing of normal tissue and less doses to OARs in carcinoma nasopharynx.

Keywords: Nasopharyngeal carcinoma (NPC), Volumetric Modulated Arc Therapy, Radiation Therapy Oncology Group.

Click here to Download Full Paper

Friday, 1 September 2017

Medical Journal: August 2017 Issue

Medical Journal: Published volume-3, Issue-7, July 2017 with ad publications

A comparative study of efficacy of micro-needling alone versus micro-needling with autologous platelet rich plasma in facial atrophic acne scars

Abstract— Post acne scarring is a consequence of abnormal resolution or wound healing following the damage that occurs in the sebaceous follicle during acne inflammation. The present study was undertaken to compare the improvement in facial atrophic acne scars by micro-needling alone and combination of micro-needling with autologous platelet rich plasma (PRP). A prospective, observer blinded, comparative interventional study was conducted on 50 patients of facial atrophic acne scars fulfilling inclusion criteria. They were randomly divided into two group of 25 each i.e. group 'A' (micro-needling alone) and group 'B' (micro-needling with PRP). Three sessions on monthly interval were conducted and Final follow up was done at 4th month. They were evaluated by Goodman and Baron’s quantitative and qualitative grading scale, for clinical improvement and for patient's satisfaction. Although qualitative and quantitative improvement was observed in both the groups but the improvement in group 'B' was more than 'A' on Goodman and Baron’s quantitative and qualitative grading scale, however it was not statistically significant. On clinical improvement and on patient satisfaction, group 'B' had better results than group 'A' which was statistically significant (p<0.05). It was concluded that Micro-needling with autologous PRP is simple, safe and cost-effective procedure for facial atrophic acne scars. Micro-needling when combined with autologous PRP provides better overall clinical improvement. It is suggested that PRP should be considered as an adjuvant therapeutic option along with micro-needling in the management of atrophic acne scars.

Keywords: Micro-needling, Goodman and Baron’s quantitative and qualitative grading scale, post acne scar, Platelet Rich Plasma (PRP).

Click here to Download Full Paper

_____________________________

Evaluation of Genetic DNA damage in the agricultural workers exposed to combined action of pesticides in Jonia area of Barpeta district of Assam

Abstract— The use of pesticide is increasing day by day and it causes a serious concern to the human health, especially some pesticides causes’ deleterious effect causing Cancer. Genotoxicity test has a special significance because it is one of the tests for cancer research and risk assessment. The sprayer has more risk because they directly cause in contact with pesticides. Pesticides may affect the DNA of the body cells of the sprayer and known to cause DNA damage. In this case control study DNA damage due to exposure of pesticides by the Agricultural workers of Jonia area of Barpeta district were assessed using the Comet assay. The result showed that the exposed workers had greater mean comet tail length than those of control i.e. 17.69±5.25 versus 10.72±7.89 (p=0.0034, t=3.8206). Among control group, smokers of exposed group have greater tail length than smokers of control group. When DNA damage in the form of comet tail length and frequency of blood leucocytes showing migration were further evaluated in study group. It was observed that although it is more in elders, vegetarian, alcoholics and smokers but it was it was found significant only in smokers than non smokers. Therefore the present studies suggest that exposure of pesticides and smoking habits may cause DNA damage.

Keywords: Agricultural workers, Pesticide, DNA damage.

Click here to Download Full Paper

____________________________

Status of oxidant and antioxidants in term newborns with hypoxic ischemic encephalopathy: A case control design

Abstract— Hypoxic ischemic encephalopathy (HIE) is due to failure to initiate and sustain breathing immediately after delivery which may leads to increase mortality and morbidity in these neonates. This may cause severe and permanent neuropsychological sequelae, including mental retardation, visual motor or visual perceptive dysfunction, increased hyperactivity, cerebral palsy and epilepsy. The brain damage may occur due to release of free radicals in HIE. So this case control study was conducted on 50 neonates with HIE and 25 healthy neonates with the aim to compare the status of oxidants and antioxidants in these both groups. It was observed that Malonyldialdehyde (MDA) was found with significantly increased in study group than control group i.e. 12.26±4.1 nmol/ml in study and 2.10±0.10 nmol/ml in control group. Among antioxidants, Catalase (30.42± 7.7 v/s 14.59± 4.7) and SOD (2.59± 0.4 v/s 1.54± 0.3) were found significantly increased whereas Vit E (1.36± 0.3 v/s 2.73± 0.6) was found significantly decreased in neonates with HIE than controls.

Keywords: Hypoxic ischemic encephalopathy (HIE), Malonyldialdehyde (MDA), Superoxide dismutase (SOD), Catalase and Vitamin E.

Click here to Download Full Paper

____________________________

Button cell battery as foreign body ingestion in children: A retrospective analysis in a tertiary care center

Abstract—Button cell foreign bodies are increasingly presented as foreign bodies in esophagus. Many a time no positive id on button cell and can be mistaken as foreign body coin and delayed for management. Retrospectively analyze of 19 admitted cases with foreign body ingestion in children for foreign body Lithium ion battery button cell in esophagus done with the aim to evaluate epidemiology, clinical presentation and duration of presentation, radiological findings, endoscopic findings and complications in such cases. Clinical record of patients with foreign body Button cell batteries was reviewed and compiled in Microsoft Excel sheet and descriptive and percentage analysis was done. There were 11 (57.89%) male patients and 8 female patients. History of foreign body battery cell was given by the parents of 10 children. 3 patients presented with respiratory complains. After history and radiological examination in 17 out of 19 patients presence of lithium cell battery was suspected prior to endoscopic removal. In 4 patients severe mucosal injury noted. It was concluded from this study that foreign body button cell can cause serious injuries to upper aerodigestive tract. These should be promptly removed.

Keywords: Foreign bodies, Button battery, Halo sign, Double rim sign.

Click here to Download Full Paper

___________________

Cardiovascular risk factors analysis in young patients with proven coronary artery disease with special reference to dyslipidemia

Abstract— Dyslipidemia is a primary, widely established as an independent major risk factor for coronary artery disease (CAD). Hence, this study was conducted with objective to find out associating risk factors in young CAD patients with special reference to dyslipidemia and its correlation of dyslipidemias & the type of obesity. A hospital Based observational descriptive study conducted on 30 patients of acute myocardial infarction below 40 years of age at department of medicine and Department of Cardiology. R.N.T. Medical College, Udaipur. To infer the association, Chi Square test in qualitative data and ANOVA & Unpaired’t’ test for quantitative data was used. Most common symptoms in young patients with acute myocardial infarction were chest pain (93.33%), Amongst risk factors smoking was most common (66.66%). The most common type of myocardial injury in ECG was anterior type of infarction in 66.66% cases. Single risk factor for myocardial infarction was present in 23.33% of patients. Two risk factors were present in 20% of patients whereas 49.9% patients had three or more risk factors. 6.6% patients had no apparent risk factors. Both BMI and waist hip ratio were abnormal in 16.66%. Dyslipidemias were observed in 46.66% cases. Hypercholesterolemia and LDL dyslipidemia was the commonest abnormality detected in both overweight and centrally obese groups.

Keywords: Coronary Artery Disease, Dyslipidemia, Risk Factors.

Click here to Download Full Paper

Thursday, 3 August 2017

Medical Journal- July issue 2017

Medical Journal: Published volume-3, Issue-7, July 2017 with ad publications

Trends of steroid modified tinea at tertiary care hospital in India

Abstract—Dermatophytes are the common fungal agents implicated in superficial skin infections worldwide, commonly known as tinea. They include species of Trichophyton, Microsporum and Epidermophyton. Infections of this organism have dramatically increased in last one decade by misuse of topical corticosteroids cream alone or in combination with topical antibacterial and antifungal agents. So this study was conducted with the aim to study about culprits (prescribers) and various offending agents. This study was conducted on 1239 consecutive patients of tinea between ages 1-70 years. Tinea was diagnosed by detailed history and clinical examination. Detailed inquiry was made for topical steroid use by recall method or relevant prescriptions. It was found that out of 1239, 1000 (80.7%) patients were using topical corticosteroid in any form. Most common age group was 21-30 years (38.3%). Pharmacist appeared as chief culprit (50.4%) and Clobetasol was major offending agent (34.8%). Majority (55.3%) of patients applied these formulations for 4 week or more. Study concluded that use of topical corticosteroids in tinea has become menace because of unethical manufacture, sales, prescription and end misuse by patient.

Keywords: Dermatophytes, Topical corticosteroids, Tinea, Culprits, Offending agents.

Click here to Download Full Paper

__________________________

Alarming tropical steroid misuse on face: A descriptive study

Abstract— Acne vulgaris is a chronic inflammatory disease of the pilosebaceous unit. The clinical lesions are non-inflammatory open and closed comedones and or papules, pustules and nodules of varying degree of inflammation and depth. A lot of steroid, cosmetic and Ayurvedic products containing unlabeled depigmenting agent and steroids are available readily over the counter sale. The side effects of these products are not documented and can lead to adverse effects of continuous usage. This study was aimed to find out various offending depigmenting agents (topical unlabeled steroid containing cosmetics) for treatment of Acne and its side effects with type of offering persons. This study was conducted on 1110 OPD patient of which 1000 (90.10%) patients are using steroid and unlabeled steroid containing cosmetics and only 110 (9.90%) patient not using any topical application. Mostly affected common age group was 11-20 years (58%) with slight female preponderance (M:F 0.96). Urban patients were more affected than rural (74% v/s 26%). Unmarrieds (76%) were more affected than married (24%). Friends appeared as chief culprit or suggestions given to them (39%) followed by family member(13.5%), self-application (12%) influenced by advertisements, chemist(11.5%), general practitioner (9.5%), neighbor (4.5%), compounder(1.5%), parlor(2%) and only 2% by dermatologist. Betamethasone (32.5%) was major offending agent followed by Clobetasol (25%), unlabeled steroid containing cosmetics (12.5%), Aloe Vera gel (7.5%). Monomorphic acne was main side effect diagnosed in 79% of patients followed by pustular acne (8%), nodular acne (4%), rosacea (4%), nodulocystic acne (3%) and perioral dermatitis (2%). Study concluded that misuse of topical steroids and unlabeled steroid containing cosmetics causing various side effects. It is unethical to sale and use without the prescription of an authorised person. So these depigmenting agents should be banned to sell without authorization and without the prescription of an authorised person.

Keywords: Acne, steroid, Culprits, Offending agent, cosmetics.

Click here to Download Full Paper

_________________________

Biochemical characteristics of Malaria patients with their association with severity of disease

Abstract— Malaria is one of the oldest and most widespread disease which affects more than 2400 million people, over 40% of world's population, in more than 100 countries in tropics from South America to Indian Peninsula. This study was designed to assess the platelet counts, haematocrit & liver enzymes (Alanine transaminase, Aspartate transaminase, Alkaline phosphatase) in patients of Plasmodium vivax & Plasmodium falciparum malaria and its association with the severity and prognosis of disease. In a hospital based observational descriptive study, 100 patients with Plasmodium falciparum and/or vivax positive diagnosed by peripheral blood film examination and/or by MPQBC (Malaria Parasite Quantitative Buffy Coat) method were included and submitted to a complete clinical & laboratory evaluation. Patients who were ≤ 14 years and who refused to give consent were excluded. They were divided into Plasmodium vivax and Plasmodium falciparum positive group; evaluated, compared and statistical analysis done. Out of total 100 cases of malaria positive, P. falciparum constituted 66% and P. vivax constituted 34%. The pathophysiological processes causing the haematological changes in malaria are complex and multiple. Thrombocytopenia presents with bleeding manifestations and it increases the severity of disease with poor prognosis.

Keywords: P. Vivax, P. Falciparum, Platelet, Haematocrit, Liver enzymes.

Click here to Download Full Paper

________________________

KIKUCHI-FUJIMOTO DISEASE (KFD): A Rare Case Report

Abstract— Kikuchi-Fujimoto disease (KFD) is a rare disease. It has a worldwide distribution with a higher prevalence in Asians. KFD is usually a self limiting disease and benign in nature. Clinically it presents as regional cervical lymphadenopathy and sometimes may presents as generalized lymphadenopathy as well. Night sweats and low grade fever may also be associated in some cases. A case of a 36 year old female had attended in SMS Hospital. She presented with fever, weight loss and tender cervical lymph nodes. Diagnostic significance of KFD lies in that it may mimic some of the common diagnosis like SLE (Systemic Lupus Erythematosis), Tuberculosis, lymphoma and rarely adenocarcinoma. Diagnosis is usually made by biopsy of lymph node which shows fragmentation, necrosis and karyorrhexis. On thorough investigation this case was found of Kikuchi-Fujimoto disease (KFD) which is a rare disease. So case presenting with fever, weight loss and tender cervical lymph nodes should also be investigated for Kikuchi-Fujimoto disease (KFD).

Keywords: Kikuchi-Fujimoto disease (KFD).

Click here to Download Full Paper

________________________

Hereditary Spherocytosis in a 17 year girl: A case report

Abstract— Hereditary spherocytosis (HS) is a familial hemolytic disorder with marked heterogeneity of clinical features, ranging from an asymptomatic condition to a fulminate haemolytic anaemia. Although a positive family history of spherocytosis increases the risk for this disorder, it may be sporadic in some cases. Seventeen years old girl presented with mild anaemia, jaundice and moderate splenomegaly. Her haematological parameters supported diagnosis of hereditary spherocytosis. Appropriate treatment was started with an advice to patient to undergo splenectomy as an active part of management of the disorder. Mother and other siblings were normal.

Keywords: Anaemia, Jaundice, Splenomegaly, Hereditary, Spherocytosis.

Click here to Download Full Paper

__________________________

Outcome analysis of Intra-articular distal end radius fracture treated with volar plating

Abstract—Fractures of distal end radius are most common fractures of the upper limb. Various techniques have been described including closed reduction, percutaneous fixation and open reduction and fixation. This study was conducted to assess the functional and radiological outcomes of volar plate osteosynthesis to manage intra-articular distal end radius fracture. For this study, 30 patients with intraarticular distal end radius fractures involving radiocarpal joint operated with open reduction and internal fixation with the volar plate were taken. Minimum follow up 6 months were done. During the follow-up, radiological parameters were assessed in terms of radial length, radial inclination, radial (palmar) tilt, articular step-off, functional parameters were assessed in terms of range of motion i.e.dorsifleion, plantar flexion, pronation, supination radial and ulnar deviation and Gartland and Werley score. Mean age of patients was 46.8 years with male: female ratio 6:4. Mean radial height was 11.2mm, mean radial inclination was 21.8 degree and mean radial (palmar) tilt was 10 degrees. Average Gartland and Werley score was 3.6. Average dorsiflexion was 71 degrees, palmar flexion was 68 degrees, mean radial deviation was 16 degrees and mean ulnar deviation was 29 degrees. Mean pronation was 72 degrees and mean supination was 75 degrees. It was concluded that volar plating has good outcome for intraarticular distal end fractures of radius with minimal complications. So, it should be considered as the first line of management for intraarticular distal end radius fracture.

Keywords: Intraarticular, Distal end Radius, Volar Plate, Gartland and Werley Score.

Click here to Download Full Paper

_____________________________

Thrombocytopenia burden and its associating Risk factors: A cross-sectional study at a tertiary care set up

Abstract—Thrombocytopenia is a very common finding in the neonatal intensive care unit. This study was designed with aim to study the risk factors associated with neonatal thrombocytopenia. In this cross-sectional observational study, 263 newborns admitted in the NICU from October 2016 to December 2016 were enrolled in the study. Proportion of thrombocytopenia was found along with its various neonatal and maternal risk factors associated. Chi-square test was used to find out association. Neonatal thrombocytopenia was found in 29% of neonates; 64 % had early onset and 36 % had late onset thrombocytopenia. Mild, moderate and severe thrombocytopenia was found in 49 %, 34 % and 17 % respectively. Thrombocytopenia was found to be associated with APH and PROM among maternal factors and with LBW, prematurity and birth asphyxia among neonatal factors.

Keywords: Thrombocytopenia, Neonatal Intensive Care Unit (NICU), Asphyxia.

Click here to Download Full Paper

___________________________

Gynecological morbidity and co-morbidity in postmenopausal women: A descriptive study

Abstract—Menopause is very crucial phase of woman’s life. There are many health problems that are associated with postmenopausal phase. So this present study was conducted on 215 postmenopausal women with the aim to find out gynecological problems associated with postmenopausal period. This study observed that 70.5% women experienced hot flushes and sweating, 65.5% had insomnia, 37.6% complained of headache. Decreased libido was observed in 80.9% women and 54.4% reported dyspareunia. 78.1% women complained of backache. Joint pain was complained by 52.5% of women. 32% women noted weight loss and 26.5% women complained of weight gain after menopause. Among gynecological problems Genital Prolapse was most common morbidity found in 45.1% of cases followed by Cancer cervix in 12.5%, Fibroid uterus in 9.3%, Senile vaginitis in 5.6%, Ovarian neoplasm in 4.1%, Cancer endometrium 1%, Pyometra in 0.9%, Carcinoma vagina 0.4% and Carcinoma vulva in 0.4% of menopausal women. Genital prolapse was found with PMB in 9.2% cases and with PMB & Vaginal discharge in 10.3% of cases.

Keywords: Postmenopausal Phase, Gynecological Problems.

Click here to Download Full Paper

__________________________

Risk factor and outcome with Gestational Diabetes Mellitus (GDM): A Cross-sectional Analysis

Abstract—Gastational diabetes Mallitus (GDM) is a condition in pregnancy which may result bad maternal and neonatal outcomes. So this study was aimed to find out various risk factors associated with GDM. This study was conducted 500 females of 2nd and 3rd trimester pregnancy. They underwent GCT (Glucose Challenge Test) with 50 gm of glucose load which was followed by GTT (Glucose tolerance test) with 75 gm glucose recommended by WHO after 72 hrs of GCT irrespective of result of GCT. Out of 500 pregnant women 27(5.4%) women are diagnosed as GDM. In women with GDM gravida ≥3, age >25 years and positive family h/o of diabetes were found with high proportion of GDM. PIH, preeclampsia and recurrent infections are most common antenatal complication seen in GDM group. It can be concluded from this that universal screening should be done for early diagnosis of GDM so complication related to tit can be controlled and bad pregnancy outcomes may be prevented.

Keywords: Gastational diabetes Mallitus (GDM), Risk factors, Pregnancy outcomes.

Click here to Download Full Paper

_______________________________

Knowledge and practice of adolescent girls about menstruation: A Cross-sectional study

Abstract— Adolescence constitutes about 20 % of world’s population. Reproductive and sexual health problems are quite common in adolescent girls in India. Bad menstruation hygiene may lead to reproductive health problems. Unsafe menstrual practices expose them to risk thrice as much of contracting RTI, therefore it is important how adolescent girls maintain hygiene during menstruation. This study was conducted to assess knowledge and practices regarding menstruation in adolescent girls. Total 376 eligible adolescent girls were studied, out of that 337 (89.62%) knew about menstruation and out of them 45.10% considered that menstruation starts at puberty, followed by physiological process (34.42%) & sign of reproductive maturity (12.46%) while 39.76% respondents thought it to be due to out flow of dirty blood. Out of 337 who knew about menstrual-cycle, only13.64% knew the fact that conception is not possible during menstrual-cycle. 59.94% respondents had prior knowledge of menarche and majority (51.54%) had this knowledge from their mothers. Out of 325 girls, who were having menstrual period, although 214 (65.84%) were using sanitary napkins but remaining 34.16% were using cloths. When association of this practice with education was evaluated it was found that above primary educated were significantly more (P< 0.001) in using sanitary napkins than girls of up to primary educated (69.47% v/s 40%). When change of material used during menstruation was asked, twice and more was answered in 194 (59.06 %), which was mot found to be associated with education (p=0.65). It was concluded that majority knew about menstruation but practice was not hygienic as they were using cloths and majority of them were less educated. So main emphasis should be given to female education.

Keywords: Adolescent Girls, Menstruation, Knowledge and Practices.

Click here to Download Full Paper

____________________***Thank you for Being with us***____________________

Medical Journal- June issue 2017

Medical Journal: Published volume-3, Issue-6, June 2017 with ad publications

Effects of Platelet Rich Plasma in Treatment of Androgenetic Alopecia (AGA): An Interventional Study

Abstract— Androgenetic alopecia (AGA) is a common condition having severe psychosocial implications. Numerous modalities of treatment are there but none is satisfactory both to the patient and the treating physician. This present study was carried out on 50 patients of AGA aged between 20 to 50 years to find out the effect of PRP with micro needling on AGA. These selected cases were treated by activation of the procedure site (scalp) by micro needling technique and application of platelet rich plasma on the activated site. A total of 6 such sittings were given to each patient at interval of 30 days each, over a total period of 6 months. Macro photographs were taken at baseline and after 6 months by 2 independent observers who rated those using of standardized seven-point rating scale of clinical change. In this study, 24% patients perceived stoppage of hair fall, 68% patients noticed reduction in hair fall, 6% of the patients perceived no change in hair fall and remaining 2% patients perceived increased hair fall after last visit with minimal or no side effects. So over all 92% patients had noticed some clinical improvement in their condition. So it was concluded that PRP with micro needling is an effective combination in treating AGA. This may be because micro needling has its own action and it would also help in promoting penetration of PRP but the level of evidence of this fact as available published data is low. This demands further studies to gain more evidence before it is used more extensively.

Keyword: Androgenetic Alopecia(AGA), Platelet Rich Plasma (PRP), Micro Needling.

Click here to Download Full Paper

____________________________

Seropositivity and seasonal trend of dengue cases in Jaipur (Rajasthan), Western India (2010-2016)

Abstract— Dengue virus infection has emerged as a notable public health problem in recent decades in terms of its increased transmission to urban and semi urban areas. Study was conducted on samples of suspected dengue cases with the aim to find out seropositivity and seasonal pattern of dengue, which is important for effective control of a disease. For this study, samples were received in department of Microbiology, SMS Hospital Jaipur (Rajasthan) for Dengue IgM & IgG during 1st January 2010 to 31st December 2016. Blood samples collected in plain vials were tested for IgM and IgG antibodies for dengue virus serotype DENV-1, 2, 3 and 4 by a solid phase in vitro immunochromatographic test. It was observed that out of 86,538 serum samples tested, 5011 (5.76 %) were found to be positive for dengue infection. Among these seven years, maximum numbers of dengue cases were identified in year 2013(33.12%). Seropositivity ranged from 0.73% in year 2016 to 13.1% in year 2010. Likewise when seasonal trend was explored it was found that 83.87% of total cases were found from September to November with peak in October. In rest of months around 1% of cases were there in each month except few more cases in August and December i.e. 4.23% and 6.25% respectively. It can be concluded that Dengue has become an endemic disease in this area. Occurrence of most of the cases in post-monsoon period indicates a need for acceleration of vector control programme prior to monsoon.

Keywords: Dengue, Seropositivity, Seasonal Trends

Click here to Download Full Paper

_________________________

Gum Hypertrophy- Warning Sign of acute myeloblastic leukemia (AML M2): A Case Report

Abstract— Many systemic diseases are early indicated by oral manifestations. Among such systemic diseases Leukemia is one which shows characteristic oral manifestations. Acute myeloid leukemia (AML) is characterized by maturation arrest of myeloid cells which leads to increase in number of myeloblasts in the bone marrow and hemopoietic insufficiency. Patients with AML in general may present with a wide variety of (atypical) symptoms, which may range from minor symptoms to life-threatening complications. Gingival hyperplasia is most commonly seen with the AML subtypes acute monocytic leukemia (M5) and acute myelomonocytic leukemia (M4). Here, an unusual case of diffuse gum hypertrophy in a 25 year old Asian female which led to laboratory studies yielding a rapid and relatively early diagnosis of acute myeloblastic leukemia (AML M2) was reported. This case emphasizes that clinicians and dentists should be well acquainted with the oral manifestations of systemic diseases and stresses the role of gingival hypertrophy as a diagnostic indicator in leukemia.

Keywords: Gingival enlargement, Leukemia, Acute Diffuse Myeloblastic.

Click here to Download Full Paper

______________________________

Outcome assessment of composite Oro-Mandibular Defect Reconstruction with Double Skin Paddle Free Fibula Osteocutaneous Flap

Abstract— Free fibular flap is the most favored free flap for composite defects of oro-mandibular region. Composite defects involving mucosa, mandible and skin often require two free flaps for the reconstruction. A technique of harvesting two separate cutaneous paddles of free fibular flap each based on a definite peroneal artery perforator was presented in this study. Reconstruction of composite oro-mandibular defect was done with two independent cutaneous paddles (proximal skin paddle based on musculo-cutaneous perforator and distal skin paddle based on septo-cutaneous perforator) in 12 patients. Post operative outcome was good, with 11 cases having no loss of skin paddle. There was an outer skin paddle necrosis in one patient for which cover was given with pectoralis major myocutanous flap. A double paddle free fibula flap can be used to reconstruct composite defects providing inner lining as well as skin cover with good flap success rates and better functional and aesthetic patient outcomes, thus avoiding an additional free or regional flap morbidity and decreased operative time.

Keywords: Oro-Mandibular Reconstruction, Free Fibula Flap.

Click here to Download Full Paper

_______________________

Fetomaternal Outcome & Complications of Pregnancy with Fibroids

Abstract—Fibroid (myoma) is the most common benign tumors of the uterus. Chances of complications are approximately 10-40% in the presence of fibroids. This study was aimed to assess the maternal & fetal outcome and complications in pregnancy with fibroids. It was conducted on 20 pregnant women with fibroid. Routine basic investigations were done for all subjects included in the study. Ultrasonography was done at booking visit and during subsequent visits to assess changes in size of the fibroid and associated complications. It was found that Fibroids were more frequent in multigravidae (65%) than primigravidae (35%). Majoriy (70%) were diagnosed as having fibroid during routine antenatal visits and 30% were known case of fibroid prior to conception. Twenty five women had pain, 10% had threatened preterm labor, 15% had spontaneous miscarriage, 30% had anemia and placenta previa was diagnosed in 15% women. Majority (60%) had Lower segment cesarean section (LSCS) and only 40% had vaginal delivery. Though many fibroids are asymptomatic but fibroids during pregnancy can lead to complications during the antepartum, intrapartum, and postpartum period, so they need proper follow-ups and repeated assessment. Overall prognosis depends on their location and size

Keywords: Fibroid, Myoma, Uterus Tumour, Fetomaternal outcome

Click here to Download Full Paper

_______________________

Hemimandiblectomy with and without intermaxillary fixation: A Quincy experiment

Abstract— Oral malignancy involving mandible, floor of mouth, tongue, and also palate when treating surgically often requires resection of mandible. Resection of mandible leads to loss of mandibular continuity, deviation of mandible towards resected site, altered mandibular movements, difficulty in swallowing, and impaired speech. Management of this type of mandibular defects without bony reconstruction is complex. Hemimandibulectomy with intermaxillary fixation prevent mandibular deviation and malocclusion.

Keywords: Intermaxillary Fixation, Hemimandibulectomy, Mandibular Deviation.

Click here to Download Full Paper

____________________

Thanatophoric Dysplasia Type I with Bilateral corneal opacities: A Case Report

Abstract— Thanatophoric dysplasia is the most common form of lethal skeletal dysplasia, diagnosed by its characteristic clinical and radiographic features. It has two types distinguished by radiological findings. Specific ocular features associated with Thanatophoric dysplasia have not known to be reported. A baby with clinical findings of a large head, short stature , low set ears, short and curved limbs, small thorax, bilateral corneal opacities and radiographs showing short and curved long bones, femurs like telephone- receiver look, H- shaped vertebrae, small iliac wings was reported. This rare case was thoroughly examined and investigated which came out to be a case of Thanatophoric Dysplasia Type I with corneal opacities. So when a case of Thanatophoric dysplasia Type 1 with bilateral corneal opacities was attended at pediatric department, a detailed report was prepared to publish such a rare case.

Keywords: Skeletal Dysplasia, Corneal Opacities.

Click here to Download Full Paper

_________________________

Anthropometric predictors for sexual dimorphism of skulls: A Comparative study

Abstract— Quantitative morphometric measurements with advanced analytical methods are emerging as reliable methods for sex differentiation of skeletal remnants. Aim of present study was to determine the difference in morphometric measurements in male and female skull and to determine the independents predictors and accuracy for sex differentiation using discriminant function analysis. A comparative observational study was conducted using 44 skull of known sex including 24skulls of males and 20 skulls of females. Various morphometric parameters are measured and analyzed using univariate, multivariate and discriminant function analysis. Cranial AP length, Bi Zygomatic diameter, Nasal Height, Nasal width and Mastoid length were found to be significantly higher in male skull. Discriminant function analysis predicted correctly the sex of skull with 79.5% accuracy. Morphometric measurement of cranium can be developed as objective method of sex determination with higher accuracy and repeatability and further enhanced by advanced statistical method like discriminant function analysis.

Keyword: Sexual Dimorphism, Morphometric Measurements, Skull.

Click here to Download Full Paper

_________________________

Acute Undifferentiated Febrile Illness (AUFI) in adult hospitalized patients: An experience from a tertiary care hospital of western Uttar Pradesh region from North India

Abstract— Acute undifferentiated febrile illness (AUFI) is a common occurrence in low and middle income groups countries like India and constitutes heavy burden on healthcare industry especially from month of June to September. AUFI includes various diseases which are very difficult to differentiate. So this study was conducted on 504 AUFI cases to present an etiological profile of these AUFI cases. It was found that among these 504 AUFI cases, 6.54% were Malaria, 15% Typhoid, 14% Dengue, 3.17% Chickenguniya, 4.56% were mixed infections and 60.7% were undiagnosed.

Keyword: Acute Undifferentiated Febrile Illness (AUFI), Malaria, Undiagnosed Undifferentiated Febrile Illness (UUFI), Dengue, Chikungunia.

Click here to Download Full Paper

________________________

Symptom Score Questionnaire for Nasolacrimal Duct Obstruction (NLDO) in Adults – A novel tool to assess impact on quality of life after Endoscopic Dacryocystorhinostomy

Abstract— Dacryocystorhinostomy (DCR) is a commonly applied surgical technique to treat nasolacrimal pathway obstruction. However, no disease-specific tools to assess the symptoms and the subjective outcome after DCR have been established. A specific Nasolacrimal Duct Obstruction Symptom Score (NLDO-SS) questionnaire was develop to evaluate the outcome and tested it in a prospective. Primary endoscopic dacryocystorhinostomy (EN-DCR) procedures were performed in 60 patients during 2013-2014. Preoperatively and during the three follow-up (3 month, 6 months and 12 months ) visits, the patients were asked to fill the NLDO-SS along with Glasgow Benefit Inventory (GBI) questionnaire. The success rate of EN-DCR was 91.67%. EN-DCR resulted in a significant reduction in all of the eight symptoms scores of the NLDO-S. The GBI scores indicated a benefit at 3 months and more benefit at 6 months, but no further improvement was found between 6 and 12 months. The correlation between the total GBI and NLDO-SS was significant. EN-DCR improves the quality of life as measured by the GBI. The NLDO-SS correlated with the GBI and gave more information about the benefits after EN-DCR than GBI alone. The NLDO-SS proved to be an effective tool to evaluate lacrimal obstructions and ENDCR benefits.

Keywords: Endoscopic Dacryocystorhinostomy, Nasolacrimal Duct Obstruction Symptom Score (NLDO-SS), Glasgow Benefit Inventory (GBI), Quality Of Life.

Click here to Download Full Paper

______________________

Cytomorphometric Study of Effect of Tobacco Smoking on Buccal Mucosa: A Case control study

Abstract—Tobacco smoking is associated with increasing risk of oropharyngeal cancer. Oral cytology, mainly based on the presence of nuclear or cytoplasmic alterations, can easily be performed to detect cancer at an early stage and provides a quantitative technique. The objective of the present study was to assess the effect of smoking on buccal mucosa using cytomorphometry. This case control study included 36 smoker subjects and 36 non-smoker controls between the age of 30 and 70 years. Buccal epithelial cells were collected with a brush and fixed smears were stained with Papanicolaou stain and cytomorphometric analysis performed using image analysis software (Image J v 1.47). Smoker group was found to have higher mean nuclear diameter (MND), lower in mean Cellular diameter (MCD), and higher nucleo-cytoplasmic ratio as compared to normal subjects. This change in nuclear parameters indicates smoking-related cellular adaptation, leading to progression towards dysplasia. Cytomorphometric changes could prove to be the earliest indicators of these cellular alterations.

Keywords: Cytomorphometry, Smoker, Buccal Mucosa.

Click here to Download Full Paper

________________________

Effect of Caudal Epidural Injection for management of Lumbar Spinal Stenosis: A randomized controlled Trial

Abstract—Chronic low back pain (LBP) is a common cause of morbidity and work absenteeism worldwide. This hospital based randomized, controlled, interventional study is conducted to assess the effectiveness of caudal epidural steroid injection in lumbar spinal stenosis. Study subjects were chronic low back pain patients attending at department of Physical Medicine and Rehabilitation (PMR), Sawai Man Singh Hospital, Jaipur (Rajasthan) India. For study purpose, 60 LBP cases were taken in Study group and 60 cases were taken for control group. To compare the effect between conservative treatment alone and added with caudal epidural injection of steroid plus saline in lumbar spinal stenosis, in study group, a mixture of MPA (3mg/kg body wt.) plus 16 ml of normal saline was injected in epidural space along with conservative treatment and in control group only conservative treatment was given. It was observed in this study that patient had more significant improvement in low back pain, leg pain, walking distance and functional activity after caudal epidural block in the study group than control group for a period of 3-6 months. So it was concluded that when conservative treatments were combined with interventional methods in form of caudal epidural steroid injection the amount of relief gets augmented as compared to the conservative treatment alone resulting in the patient benefiting in terms of much better symptom control and pain relief, improvement in anxiety, depression and activity limitations and quality of life.

Keywords: Chronic low back pain (LBP), Methylprednisolone Acetate.

Click here to Download Full Paper

Medical Journal- May issue 2017

Medical Journal: Published volume-3, Issue-5, May 2017 with ad publications

Chikungunya fever in children: A Descriptive Study

Abstract—In the Indian sub-continent, first isolation of the chikungunya virus was done in Kolkata during 1963. During 2006 reports of large scale outbreaks in several parts of India have confirmed the re-emergence of this virus in the country. Since the incidence of this disease is increasing. So a retrospective analysis of laboratory confirmed chikungunya patients admitted to pediatric ward was done to study biochemical profile of chikungunya fever in children. Total 51 children were laboratory confirmed for chickungunya, 36 of them had isolated chikungunya infection. Male/female ratio of isolated chikungunya was 2.6:1. Fever was invariably present, associated constitutional symptoms consisted of skin rash, vomiting, diarrhea, pain abdomen, cough, corrhyza, myalgia and bleeding manifestations. The most characteristic feature of the infections in infants was skin manifestations in form of symmetrical superficial vesiculobullous lesions & maculopapular erythematous rash. Nine patients (25%) had neurological manifestations. Joint pain was present in only three patients but none had arthritis. Most common hematological abnormality revealed thrombocytopenia in 39% cases. There was mild to moderate elevation of liver enzymes in 13 patients (36%). Average length of hospital stay was 5.1 days. Thirty four patients recovered completely & two left against medical advise. It is concluded from this study that skin manifestations and neurological manifestations are common in younger age group apart from other constitutional symptoms. Arthralgia and chronic polyarthritis is rare in this age group as found in adults.

Keyword: Chikungunya in Children; Viral Fever; Vesiculobullous Lesions.

Click here to Download Full Paper

_________________________

Paraquat Poisoning (Lethal Herbicide):A Rare Case Report

Abstract— Paraquat, chemically 1, 1’ dimethyl-4-4’-bipyridinium, is a green colored herbicide. It is one of the most lethal herbicide and is hazardous in very small quantities. More than 93% of deaths by paraquat are suicidal in nature. Poisoning by paraquat is commoner in developing countries because of agriculture based economy. The presentation of paraquat poisoning varies from case to case and depends on the amount consumed. As the compound is highly lethal, an early suspicion & management is must to prevent complications. Present case is of paraquat poisoning with full blown early picture of mucosal ulceration, pneumonitis and acute kidney injury which later on complicated in esophageal perforation, pneumothorax and pneumomediastinum.

Keywords: Paraquat, AKI, Pneumomediastinum, Pneumonitis.

Click here to Download Full Paper

____________________________

Perinatallethal Osteogenesis Imperfecta Type II A with white sclerae:A Case Report

Abstract— Osteogenesis Imperfecta is a genetic connective tissue disorder. It has clinically heterogeneous four types. Type 2 is the most severe and perinatally lethal form having small thorax, curved limbs and blue/gray sclerae. It is further subclassified into 3 types. A baby with sign and symptoms with macrocephaly, retrognathia, low set ears, widely placed eyes with white sclerae, complete cleft palate, narrow chest, curved and shortened limbs, B/L CTEV, left undescended testis with hypospadiasis was reported. This rare case was thoroghly examined and investigated which came out to a case of 'Osteogenesis Imperfecta type 2 A' having white sclerae. So case having such symptoms were should be investigated for Osteogenesis Imperfecta.

Keywords: Osteogenesis Imperfecta Type 2, White Sclerae, Genetic disorder, Perinatally lethal condition.

Click here to Download Full Paper

_________________________

Fungal infections in Otorhinolaryngology: A Descriptive Study

Abstract—Fungal organisms are ubiquitous. A common location for these organisms to enter the human body is through the external acoustic canal, oral cavity, and pharynx and sino-nasal cavity. A study was conducted with clinical and mycological analysis of various fungal infections in ENT. Patients suspected for having fungal infections attending at Department of ENT were interrogated and analysed. Swabs collected from these cases were sent for direct microscopy by KOH mounts for fungal examination and fungal culture. Microbiological confirmed 100 cases were finally included in the study Histopathological examination of nasal mass and polyposis was also done. It was observed in this present study otomycosis was most common and accounted for 84% of the total cases followed by candidiasis in oral cavity and pharynx in 9%, allergic fungal rhinosinusitis in 4% and rhinosporidiosis in 3%. Aspergillus niger was that most common fungus isolated in 61% cases, followed by Candida albicans in 24% cases, Aspergillus flavus in 9% cases, Aspergillus fumigatus and Rhinosporodium seeberi in 3% cases each. All the cases of fungal infection of oral cavity and oropharynx were due to Candida albicans.

Keyword: Fungal infection, Otomycosis, Aspergillus, Candida.

Click here to Download Full Paper

________________________

Variation in origin of Lateral Circumflex Femoral Artery: A Case Report

Abstract— Profunda femoris artery and its branches are extensively used in different diagnostic and therapeutic interventions. Knowledge about the anatomical variations is important to prevent iatrogenic complications. During routine dissection for teaching medical graduates, a variant vascular pattern of lateral circumflex femoral arteries was observed in an adult cadaver. The Lateral Circumflex Femoral Artery was found to be arising directly from the Femoral Artery on its posterior aspect, 7.0 cm distal to the inguinal ligament on the left side.

Keywords: Profunda Femoris Artery, Lateral Circumflex Femoral Artery, Femoral Artery.

Click here to Download Full Paper

____________________________

Effect of Agave sisalana Perrine extract on the ovarian and uterine tissues and fetal parameters: Comparative Interventional Study

Abstract— Agave sisalana (Agavaceae), commonly known as sisal plant has an anti-inflammatory, analgesic, anthelmintic, bactericidal and insecticidal activities. Its toxic effects on female reproduction are unknown. This comparative interventional study aimed to assess the ovarian and uterine tissues and fetal parameters of rats treated with the extract of sisal waste (100 mg kg-1 body weight), obtained from decortications of the A. sisalana. The control received distilled water. The treatments were performed orally for 30 consecutive days. The results showed that the estrous cycle and ovarian tissue were not affected by plant extract. There was an significant increase (p<0.05)in the thickness of perimetrium in females treated with A. sisalana. The placental and litter weights also increased significantly whereas the litter size significantly decreased (p<0.05) in the group receiving the extract. In conclusion, A. sisalana showed no pathological changes in the ovaries and uterine endometrium, but had a negative effect on the litter size and weight.

Keywords: Sisal, Gonadotoxicity, Reproduction Fetotoxicity.

Click here to Download Full Paper

_____________________________

Bio-Socio-demographic Risk factors of Gestational Diabetes: A Case Control Study

Abstract—India is second largest country to have people with Diabetes Mellitus (DM) in world. Gestational Diabetes Mellitus (GDM) has bad pregnancy outcomes so this present case control study was conducted on 50 pregnant women (ANCs) with GDM and 50 normal ANCs to assess the bio-socio-demographic risk factors of Gestational Diabetes. It was found that GDM was significantly associated with age, religion, residence and BMI of woman. GDM was found significantly more with increasing age and increasing BMI. ANCs residing in urban areas and belonging to Muslim religion were more pron to have GDM than their counter parts. Family history of diabetes also favors in occurrence of GDM. So clinicians should increase GDM screening at first ANC visit and prompt treatment is recommended to prevent complication. Early identification of woman at risk of GDM may prevent maternal and perinatal morbidity.

Keyword- Gestational Diabetes Mellitus, Risk factors, Impaired Glucose Tolerance, Bio-socio-demographic factors.

Click here to Download Full Paper

Monday, 1 May 2017

IMJ Health April 2017

Medical Journal: Published volume-3, Issue-4, April 2017 with ad publications

Lipid Profile in Subclinical Hypothyroidism: A Case-control Study

Abstract—Subclinical Hypothyroidism is a much more common disorder with a world-wide occurrence as compared to overt Hypothyroidism. Overt Hypothyroidism is associated with abnormalities of lipid metabolism, but the significance of dyslipidemia in subclinical hypothyroidism (SCH) remains controversial.

Aims: To compare the lipid profile between subclinical hypothyroid patients & healthy controls (age & sex matched) so as to determine any association between lipid profile & subclinical hypothyroidism.

Materials and Methods: In a case-control study, Thyroid stimulating hormone (TSH), free T3, free T4, anti thyroperoxidase (TPO) antibodies, total cholesterol, high density lipoprotein(HDL) cholesterol, low density lipoprotein (LDL) cholesterol, Very low density lipoprotein (VLDL) cholesterol, serum triglycerides were measured in 50 patients with subclinical hypothyroidism and 50 age- and sex-matched Euthyroid controls after an overnight fasting.

Results: Mean serum triglycerides (TG) and very low-density cholesterol (VLDL) were significantly higher in patients with SCH than controls (P < 0.05). No association was found between serum total cholesterol, high density lipoprotein (HDL) cholesterol, low density lipoprotein (LDL) cholesterol and SCH.

Conclusions: Dyslipidemia is more common in SCH compared to controls. High serum triglycerides and VLDL were observed in patients with SCH.

Keywords: Subclinical hypothyroidism (SCH), TSH, Lipid Profile.

Click here to Download Full Paper

_____________________________

Disseminated Intra-Abdominal Hydatidosis: A Case Report

Abstract—Hydatid cyst disease is a zoonotic disease caused by the larval stage of Echinococcus granulosus and Echinococcus Multilocularis. In human beings, apart from involving the liver and lungs commonly, it also affects other organs like brain, kidney and spleen. Rupture of Hydatid cyst into abdominal cavity causes disseminated abdominal hydatidosis which is a rare complication. Here this rare case was presenting as a 48 years old female patient of disseminated intra-abdominal hydatidosis. Disseminated abdominal hydatidosis occurs secondary to traumatic or surgical rupture of a hepatic cyst. Ultrasonography or Computed Tomography findings are helpful in making a definitive diagnosis. For localized hydatid cysts in liver or lungs, the management of choice is preferably surgical while the treatment for disseminated intra-abdominal hydatidosis remains medical. Albendazole is the treatment of choice for disseminated abdominal hydatidosis.

Keywords: Zoonotic, Disseminated, Abdominal, Hydatid Cyst

Click here to Download Full Paper

__________________________

Immune Reconstitution Inflammatory Syndrome (IRIS) Associated Multifocal Leukoencephalopathy (PML) in Patients with Human Immunodeficiency Virus (HIV) Infection: A Case Report

Abstract—Progressive Multifocal Leukoencephalopathy (PML) is seen mostly in advanced human immunodeficiency virus (HIV) infection. In some individuals, especially those with very low CD4+ counts, worsening of PML or new-onset PML can be observed after the initiation of highly active antiretroviral therapy (HAART). A case of IRIS associated PML is reported here which is much more rare as compared to PML in HIV patients unrelated to HAART. This is thought to be secondary to immune reconstitution inflammatory syndrome (IRIS). IRIS is defined as a paradoxical deterioration of a previously existing infection which is related to the immune system recovery. It is suggested to occur due to an imbalance of CD8+/CD4+ T cells. So in HIV cases with low CD4 counts and if one is on HAART then should be further investigated for IRIS and PML.

Keywords: PML, HIV, HAART, IRIS

Click here to Download Full Paper

_________________________

Role of 3-Dimensional Sonohysterography in Infertility

Abstract—3D ultrasound (3-dimensional sonography) when combined with sonosalpingography, it provides detailed information regarding internal and external contours of the uterus, without the need for radiation contrast material or surgical intervention. This study was done because of the need of such diagnostic modality that is highly accurate as well as least invasive. A descriptive study was conducted on 50 infertile females to assess the diagnostic value of 3-dimensional SHG in reference of diagnostic hystero-laproscopy (DHL) assuming as gold standard. It was found that sensitivity of 3-dimensional SHG reasons of tubal patency, ovarian pathology and uterine cavity was found 97.6%, 90.91% and 71.43% respectively. And diagnostic accuracy of 3-dimensional SHG in reference of DHL for tubal patency, ovarian pathology and for uterine cavity was found 96%, 92% and 96% respectively. So it can be concluded from present study that 3-Dimensional sonohysterography is an efficient tool to assess women with infertility. Its sensitivity, specificity, and diagnostic accuracy is comparable to hysterolaproscopy.

Keywords: Infertility, 3-dimensional SHG (SHG), Diagnostic Hystero-Laproscopy (DHL), Diagnostic Values.

Click here to Download Full Paper

_________________________

Medial Temporal Lobe Encephalitis associated to Chikungunya Virus Infection: A Case Report during First Epidemic in Americas

Abstract—Chikunguniya can be associated with encephalitis which is a rare complication of chikunguniya. Such a rare case was attended at National University Hospital (Hondura) in August 2015, which was studied in detail. A 64 years, Honduran patient was admitted during the convalescent period of an acute febrile illness with arthralgias one month prior. Two weeks later, he developed a severe inability to form new memories disorientation to date and time; forgetting family member´s names and daily routines. The patient exhibited spontaneous crying and sadness. Premorbid cognitive, behavioral and functional abilities were normal. Patient was evaluated and investigated. On investigation Chikungunya IgM antibodies were positive and on Brain MRI revealed predominantly right medial temporal lobe hyperintensities in Diffusion weighed images; also seen in FLAIR sequences. Patient was confirmed as Chikunguniya case associated with medial temporal lobe encephalitis. So it is suggested that patients presenting with a rapidly evolving amnestic syndrome after an acute febrile illness with polyarthralgias in an endemic region should be tested for the Chikungunya virus. More cases must be described and studied, however, to better characterize this condition.

Keywords: Temporal Lobe, Encephalitis, Chikungunya.

Click here to Download Full Paper